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House GOP leaders are working on a bill to approve more funding for the fight against the Zika virus by the end of the year as they face mounting pressure from the White House.

The Na­tion­al In­sti­tutes of Health has some lofty goals: at­tempt­ing to cure can­cer and in­di­vidu­al­ize dis­ease treat­ments, es­tab­lish­ing a one mil­lion-plus re­search co­hort, and re­vo­lu­tion­iz­ing how sci­ent­ists un­der­stand the hu­man brain.

Senior U.S. House of Representatives Republican Tom Cole said on Wednesday more funds will be needed to fight the Zika virus in the United States, signaling a shift from insistence by many Republicans that the Obama administration should use existing funds for the effort to combat the growing threat.

Two months ago, the Obama administration asked for roughly $1.9 billion in emergency funding to combat the Zika virus. Public-health officials were eager to get money for vaccine research and more. “We are hopeful that Congress will recognize the urgency of this request and act quickly on it,” White House Press Secretary Josh Earnest said at a February briefing, accompanied by health-agency officials. “This sort of falls in the category of things that shouldn’t break down along party lines.

Just months into the job, House Speaker Paul Ryan is winning praise from his GOP colleagues by finding ways to bring President Obama to heel in his last year in office, like forcing new certification deadlines on the government and challenging Obama personally when he disagrees with how federal officials implement laws.